People recognized Jizera River over ten thousand years ago. The Celts called Isora – Sharp River, and the Slavs changed the name to Jizera. Identically to other rivers, it has always been the centre of living. At first, the commerce routes passed through the river valley which resulted in the formation of settlements. The settlement formation gradually continued in higher locations accompanied by the development of non-agricultural style of living which resulted in higher utilization of the river natural corridor. The routes were replaced with the paths, later with the roads for carriages, roads, and with railway in the 19th century. The river is further used for sources of power. Water has been restricted by means of weirs, factories and power plants have been constructed.